Stability-Indicating High-Performance Thin-Layer Chromatographic Method for Quantitative Estimation of Emtricitabine in Bulk Drug and Pharmaceutical Dosage Form

Table 3

Robustness testing (𝑛=6).

Parameter	SD of peak area^a	RSD^a%
Mobile-phase composition (±0.1 mL)	1.34	0.24
Amount of mobile phase (±5%)	2.19	0.49
Time from spotting to chromatography (+10 min.)	1.29	0.18
Time from chromatography to scanning (+10 min.)	1.12	0.09

^aAverage of three concentrations 70, 90, 110 ng spot⁻¹ for emtricitabine.