Fluorometric Determination of Drugs Containing α-Methylene Sulfoxide Functional Groups Using 𝑁¹- Methylnicotinamide Chloride as a Fluorogenic Agent

Table 8

Results of the proposed method recovery experiments of 1–5 of different pharmaceutical preparations.

Drug	Pharmaceutical preparations	% recovery ± S.D.*
1	Rudac 150 mg tablet	102±0.56%
	Rudac 200 mg tablet	101±2.1%
	HiDac 200 mg tablet	98.5±1.55%
2	Epirazole 20 mg capsule	100.1±1.37%
	Gastrozole 20 mg capsule	100±0.95%
	Gastrocure 20 mg capsule	99±1.22%
	Napizole 20 mg capsule	98.45±0.88%
	Omepak 20 mg capsule	99.98±1.56%
	Omepak 10 mg capsule	100±1.11%
	Ulstop 20 mg capsule	97.9±0.99%
	Gasec 20 mg capsule	100.2±1.52%
	Risek 20 mg capsule	98±1.63%
	Pepzole 40 mg capsule	97.88±0.54%
	Gastroloc 40 mg capsule	97.2±0.55%
	Omepral 20 mg capsule	99±1.42%
	Omez 10 mg capsule	99.9±0.78%
	Trio 20 mg capsule	98.1±1.74%
	Nexium 20 mg (esomeprazole magnesium tablet)**	96.12±0.56%
3	Lansoprazole 30 mg cap	100.6±2.31%
	Zollipak 30 mg cap	101±1.51%
	Peptazole 30 mg cap	99±2.1%
	Lanzor 15 mg cap	100.1±1.2%
	Lanzor 30 mg cap	99.8±0.95%
	Lopral 30 mg cap	99±0.89%
4	Controloc 20 mg tablet	98±1.98%
	Pantoloc 20 mg tablet	97±0.51%
	Pantoloc 40 mg tablet	101±1.12%
	Pantazole 40 mg tablet	101.5±0.52%
5	Bepra 20 mg tablet	102±1.35%
	Pariet 20 mg tablet	100±2.1%

*Average of triplicate analyses.
** The (S)-enantiomer of omeprazole; the pharmacologically active form.