Table 2: Pharmacokinetics of insulin preparations.

Type of insulin OnsetPeak (hours)Duration (hours)

Rapid analogs (lispro, aspart, glulisine)5–15 minutes1-24–6
Short (regular)30–60 minutes2-36–10
Intermediate (NPH*)2–4 hours4–1012–18
Long (glargine)2–4 hoursFlat20–24
Long (detemir)2 hoursFlat6–24

*NPH: Neutral Protamine Hagedorn.