Organ-Based Response to Exercise in Type 1 Diabetes
Figure 2
(a) Immunofluorescence staining for the calcium-pump, SERCA2, illustrates high levels of the protein distributed throughout the cell from a healthy nondiabetic animal. (b) In an age-matched, immune-mediated diabetic animal (7 weeks of diabetes), the SERCA2 levels were lower in the cell, and the SERCA distribution was punctate with a strong perinuclear localization. Scale bar = 5 μm. Images generously provided by Dr. Yvonne Searls, University of Kansas Medical Center.
