Clinical Study

Primary Sclerosing Cholangitis Associated with Elevated Immunoglobulin-G4: A Preliminary Study

Table 2

Demographic clinical, and laboratory features in the IAC patients. Laboratory parameters are demonstrated as median and IQR.

Patients with PSC with IgG4 elevation (IAC) ( 𝑛 = 9 )

Age, years45 (21–60)
Gender (male)7 (77.8%)
Smoking4 (44.4%)
IBD Present3 (33.3%)
High CA 19-97 (77.8%)
AMA ( ± )0
ASMA ( ± )1 (11.1%)
ALKM ( ± )0
Intrahepatic involvement (MRCP)5 (55.6%)
Extrahepatic involvement (MRCP)1 (11.1%)
IgG4 (10–157 mg/dL) 2 1 8 . 0 0 ± 4 6 . 3 3
(159–292 mg/dL)
Hb 1 2 . 5 8 ± 1 . 8 7 (8–14.4)
AST (<40 U/L) 7 5 . 4 4 ± 5 1 . 8 5 (27–160)
ALT (<40 U/L) 6 9 . 8 8 ± 5 1 . 0 8 (19–160)
Alk Ph (<200 U/L) 6 6 4 . 1 1 ± 3 2 8 . 2 9 (327–1436)
Bil total (<2 mg/dL) 2 . 8 2 ± 2 . 5 3 (0.4–6.90)
Bil direct (<2 mg/dL) 1 . 8 4 ± 2 . 2 1 (0.1–5.8)