H19-Promoter-Targeted Therapy Combined with Gemcitabine in the Treatment of Pancreatic Cancer
Figure 2
Histopathology analyses in orthotopically induced tumors in the pancreas of hamsters treated either with Luc-H19 + gemcitabine (a) or BC-819 + gemcitabine. (b) The arrows in pictures (a) and (b) mark the necrotic area (X10 original magnification for picture). An extensive area of necrotic tissue it is clearly shown in the BC-819-gemcitabine-treated tumor only. Slides were prepared from paraffin block sections and stained with hematoxylin eosin.