Figure 8: Simulations based on a nonperiodic and a periodic MAPK pathway model are shown on the lefthand and the righthand side, respectively. Comparisons between the differential equation system and a greedy (ab) and a hierarchical (cd) abstraction approach are shown. The results of the DE model are indicted by dashed lines, the agentbased dynamics are depicted as shaded areas. The numbers of agents deployed by the abstraction approaches are compared in (e) and (f) (individual legends are provided in these two diagrams). 
