Efficient Nonviral Gene Therapy Using Folate-Targeted Chitosan-DNA Nanoparticles In Vitro
Figure 2
Agarose gel electrophoresis. (a) Chitosan nanoparticles with VR1412 β-gal plasmid DNA. (b) Chitosan nanoparticles with GFP plasmid DNA. Lane 1: ladder; lane 2: naked DNA; lane 3: Ch-DNA nanoparticule with a Mw = 5 KDa chitosan; lane 4: Ch-PEG-FA-DNA nanoparticule with a Mw = 5 KDa chitosan; lane 5: Ch-DNA nanoparticule with a Mw = 25 KDa chitosan; lane 6: Ch-PEG-FA-DNA with a Mw = 25 KDa chitosan; lane 7: Ch-DNA with a Mw = 50 KDa chitosan; lane 8: Ch-PEG-FA-DNA nanoparticule with a Mw = 50 KDa chitosan.
