About this Journal Submit a Manuscript Table of Contents
ISRN Spectroscopy
Volume 2012 (2012), Article ID 373215, 6 pages
http://dx.doi.org/10.5402/2012/373215
Research Article

Simple Methods for the Spectrophotometric Determination of Carvedilol

Department of Post Graduate Studies and Research in Chemistry, Mangalore University, Mangalagangothri, Karnataka, Mangalore 574 199, India

Received 30 August 2012; Accepted 14 October 2012

Academic Editors: F. Cataldo, C. Kosmidis, and G. Schenk

Copyright © 2012 Divya N. Shetty and B. Narayana. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. B. T. Vanderhoff, H. M. Ruppel, and P. B. Amsterdam, “Carvedilol: the new role of beta blockers in congestive heart failure,” American Family Physician, vol. 58, no. 7, pp. 1627–1639, 1998. View at Scopus
  2. F. Varin, L. X. Cubeddu, and J. R. Powell, “Liquid chromatographic assay and disposition of carvedilol in healthy volunteers,” Journal of Pharmaceutical Sciences, vol. 75, no. 12, pp. 1195–1197, 1986. View at Scopus
  3. N. Hokama, N. Hobara, H. Kameya, S. Ohshiro, and M. Sakanashi, “Rapid and simple micro-determination of carvedilol in rat plasma by high-performance liquid chromatography,” Journal of Chromatography B, vol. 732, no. 1, pp. 233–238, 1999. View at Publisher · View at Google Scholar · View at Scopus
  4. P. Ptáček, J. Macek, and J. Klíma, “Liquid chromatographic determination of carvedilol in human plasma,” Journal of Chromatography B, vol. 789, no. 2, pp. 405–410, 2003. View at Publisher · View at Google Scholar · View at Scopus
  5. E. J. Eisenberg, W. R. Patterson, and G. C. Kahn, “High-performance liquid chromatographic method for the simultaneous determination of the enantiomers of carvedilol and its O-desmethyl metabolite in human plasma after chiral derivatization,” Journal of Chromatography, vol. 493, no. 1, pp. 105–115, 1989. View at Publisher · View at Google Scholar · View at Scopus
  6. R. Rathod, L. P. C. Prasad, S. Rani, M. Nivsarkar, and H. Padh, “Estimation of carvedilol in human plasma by using HPLC-fluorescence detector and its application to pharmacokinetic study,” Journal of Chromatography B, vol. 857, no. 2, pp. 219–223, 2007. View at Publisher · View at Google Scholar · View at Scopus
  7. R. Gannu, V. V. Yamsani, and Y. M. Rao, “New RP-HPLC method with UV-detection for the determination of carvedilol in human serum,” Journal of Liquid Chromatography and Related Technologies, vol. 30, no. 11, pp. 1677–1685, 2007. View at Publisher · View at Google Scholar · View at Scopus
  8. L. Clohs and K. M. McErlane, “Comparison between capillary electrophoresis and high-performance liquid chromatography for the stereoselective analysis of carvedilol in serum,” Journal of Pharmaceutical and Biomedical Analysis, vol. 31, no. 3, pp. 407–412, 2003. View at Publisher · View at Google Scholar · View at Scopus
  9. H. Y. Wang, Y. Xiao, J. Han, and X. S. Chang, “Simultaneous determination of dopamine and carvedilol in human serum and urine by first-order derivative fluorometry,” Analytical Sciences, vol. 21, no. 11, pp. 1281–1285, 2005. View at Publisher · View at Google Scholar · View at Scopus
  10. A. Radi and T. Elmogy, “Differential pulse voltammetric determination of carvedilol in tablets dosage form using glassy carbon electrode,” Farmaco, vol. 60, no. 1, pp. 43–46, 2005. View at Publisher · View at Google Scholar · View at Scopus
  11. H. S. Yathirajan, S. Bindya, T. V. Sreevidya, B. Narayana, and M. Bolte, “A second polymorph of carvedilol,” Acta Crystallographica Section E, vol. 63, no. 2, pp. o542–o544, 2007. View at Publisher · View at Google Scholar · View at Scopus
  12. P. S. Jain, G. S. Talele, S. G. Talele, and S. J. Surana, “Spectrophotometric determination of carvedilol from bulk and formulations,” Indian Journal of Pharmaceutical Sciences, vol. 67, no. 3, pp. 358–359, 2005. View at Scopus
  13. G. Chaurasia, D. Bhadra, S. Bhadra, and N. K. Jain, “UV spectrophotometric determination of carvedilol,” Indian Journal of Pharmaceutical Sciences, vol. 67, no. 5, pp. 606–608, 2005. View at Scopus
  14. J. Verma and H. Syed, “Extractive spectrophotometric method for determination of carvedilol in tablets,” Indian Journal of Pharmaceutical Sciences, vol. 69, no. 2, pp. 303–304, 2007. View at Scopus
  15. T. V. Sreevidya and B. Narayana, “Simple and facile methods for the determination of carvedilol in Pharmaceuticals,” Indian Journal of Chemical Technology, vol. 16, no. 1, pp. 74–78, 2009. View at Scopus
  16. J. N. Miller and J. C. Miller, Statistics and Chemometrics for Analytical Chemistry, Prentice Hall, 4th edition, 2005.