Research Article
Nephroprotective Effect of Ursolic Acid in a Murine Model of Gentamicin-Induced Renal Damage
Table 3
Histopathological features of kidneys of rats of different treatment groups.
| | Histopathological feature | Control group | Gentamicin group | Ursolic acid
2 mg/kg | Ursolic acid
5 mg/kg | Ursolic acid
10 mg/kg |
| | Glomerular congestion | — | 4 | 2 | 1 | 1 | | Blood vessel congestion | — | 3 | 2 | 1 | 1 | | Interstitial edema | — | 3 | 1 | 1 | 0 | | Inflammatory cells | — | 2 | 1 | 2 | 0 | | Necrosis and tubular casts | — | 4 | 2 | 1 | 0 | | Average score | 0 | 3.2 | 1.6 | 1.2 | 0.4 |
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