Stability-Indicating HPTLC-Densitometric Method for Estimation of Dorzolamide Hydrochloride in Eye Drops

Table 3

Robustness testing.

Parameters	SD of peak area	% RSD
Mobile-phase composition (±0.1 mL)	28.3	0.91
Amount of mobile phase (±5%)	41	0.33
Plate pretreatment (4, 5, 6 min)	1.2	0.02
Time from spotting to chromatography (+10 min)	0.5	0.07
Time from chromatography to scanning (+10 min)	0.08	0.01

^an = 6.