Research Article

Stability-Indicating HPTLC-Densitometric Method for Estimation of Dorzolamide Hydrochloride in Eye Drops

Table 7

Summary of validation parameters.

ParameterDORZO

Linearity range (ng/spot)100–500
Correlation coefficient0.9992 ± 0.04
Limit of detection (ng/spot)30
Limit of quantitation (ng/spot)95
Recovery (n = 6)99.42
Precision (% R.S.D.)
 Repeatability0.08
 Intermediate1.68
RobustnessRobust
SpecificitySpecific