Relation of High-Density Lipoprotein Cholesterol and Apoprotein A1 Levels with Presence and Severity of Coronary Obstruction

Table 1

Distribution of lipid parameters in Group 1 (patients presenting a ≥50% diameter stenosis in at least one major coronary artery) and Group 2 (patients who had no significant obstructions).

	Group 1 (𝑛=659)	Group 2 (𝑛=239)	𝑃
Lipids (mg/dL)
Total cholesterol	182.84 (42.71)	188.12 (41.65)	NS
HDLc	44.35 (12.08)	48.75 (13.30)	0.001
Triglycerides	131.62 (90.43)	123.45 (61.19)	N.S.
LDLc	112.97 (36.40)	115.27 (35.65)	N.S.
apoB	99.94 (26.61)	99.18 (26.10)	N.S.
apoA1	132.37 (26.36)	141.21 (25.71)	0.001
Non-HDLc	138.69 (40.03)	139.37 (39.67)	N.S.
Ratios
CT/HDLc	4.36 (1.33)	4.07 (1.17)	0.005
LDLc/HDLc	2.70 (1.07)	2.49 (0.95)	0.015
apoB/apoA1	0.78 (0.25)	0.73 (0.23)	0.003

HDLc: high-density lipoprotein cholesterol; LDLc: low-density lipoprotein cholesterol; apo: apolipoprotein.
Parametric variables are expressed as mean (standard deviations); 𝑃 values for differences between the two groups were determined by Student’s 𝑡-test.