Clinical Study

Relation of High-Density Lipoprotein Cholesterol and Apoprotein A1 Levels with Presence and Severity of Coronary Obstruction

Table 2

Basal characteristics and distribution of lipid parameters between groups A, B, and C (single, double, and triple vessel disease, resp.).

Group A ( 𝑛 = 2 2 8 )Group B ( 𝑛 = 2 5 4 )Group C ( 𝑛 = 1 7 7 ) 𝑃

Age (years)63.40 (11.55)66.39 (11.21)66.92 (10.88)0.002
BMI (kg/m2 )28.14 (4.10)27.70 (3.74)27.45 (3.72)NS
Smokers (%)29.625.925.4NS
Hypertension (%)61.461.464.0NS
Dyslipidemia (%)61.968.363.6NS
Diabetes (%)31.332.142.10.051
Lipid parameters
Non-HDLc137.82 (38.22)136.62 (38.90)142.33 (43.41)N.S.
TC/HDLc4.25 (1.31)4.28 (1.25)4.53 (1.35)0.097
LDL/HDLc2.62 (1.06)2.65 (0.99)2.81 (1.10)0.200
apoB/apoA0.75 (0.25)0.78 (0.25)0.81 (0.26)0.073

Group A: patients with stenosis ≥ 50% in a vessel; Group B: patients with stenosis ≥ 50% in two vessels; Group C: patients with stenosis ≥ 50% in three vessels; HDLc: high-density lipoprotein cholesterol; LDLc: low-density lipoprotein cholesterol. Quantitative variables are expressed as percentages; Pearson Chi-square was used to determine 𝑃 values; quantitative variables are expressed as mean (standard deviation), 𝑃 values were determined by ANOVA test.