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Research Article

Effects of Aqueous Extract of Fresh Leaves of Abroma augusta L. on Oral Absorption of Glucose and Metformin Hydrochloride in Experimental Rats

Table 1

Blood glucose level (mmol/L) after oral administration of glucose, WSF of A. augusta L. and CMC in rats kept for fasting for 24 hrs.
Blood glucose level (mmol/L)
Treatment groups0 hr2 hrs4 hrs8 hrs12 hrs24 hrs
NC 6 . 3 0 ± 0 . 4 2 5 . 8 0 ± 0 . 2 8 5 . 3 5 ± 0 . 9 2 6 . 2 0 ± 0 . 8 5 7 . 7 5 ± 3 . 1 8 5 . 2 5 ± 0 . 3 5
FC 4 . 1 0 ± 0 . 1 4 4 . 0 ± 0 3 . 7 5 ± 0 . 2 1 3 . 2 0 ± 0 . 2 8 3 . 1 0 ± 0 . 1 4 3 . 0 ± 0
FG 4 . 0 ± 0 4 . 2 5 ± 0 . 0 7 4 . 7 0 ± 0 . 1 4 3 . 6 0 ± 0 . 1 4 3 . 2 5 ± 0 . 0 7 3 . 4 0 ± 0 . 2 8
FGC 4 . 4 0 ± 0 . 7 1 3 . 9 0 ± 0 . 2 8 3 . 6 0 ± 0 . 5 7a 3 . 4 0 ± 0 . 4 2 3 . 2 0 ± 0 . 1 4 3 . 7 5 ± 0 . 0 7
FGF 6 . 7 0 ± 1 . 2 7 4 . 3 0 ± 0 3 . 4 0 ± 0 . 5 7a 3 . 6 0 ± 0 . 4 2 3 . 7 5 ± 0 . 6 4 3 . 1 0 ± 0 . 1 4
Values are expressed as mean ± SD of three replicates. NC: normal control; FC: fasting control; FG: fasting with glucose (1.2 gm/kg b. w.); FGC: fasting with glucose and CMC; FGF: fasting with glucose (1.2 gm/kg b. w.); WSF of A. augusta L. a 𝑃 < 0 . 0 5 compared to FG (ANOVA followed by Dunnett’s test).