Effects of Aqueous Extract of Fresh Leaves of Abroma augusta L. on Oral Absorption of Glucose and Metformin Hydrochloride in Experimental Rats

Table 2

Blood glucose level (mmol/L) in alloxan-induced diabetic rats after oral administration of metformin, WSF of Abroma augusta L. and CMC.

Blood glucose level (mmol/L)
Treatment groups	0 hr	2 hrs	4 hrs	8 hrs	12 hrs	24 hrs
NC	7.77±1.49	6.46±0.52	5.60±1.27	6.75±1.77	6.30±1.84	6.90±1.41
DC	30.85±3.32	30.85±3.75	31.45±3.32	31.75±3.04	32.15±2.62	32.80±1.70
MC	32.80±0.42	25.45±1.20	21.05±0.35	18.80±0.56	23.0±0.14	25.60±1.56
DMC	33.20±0.84	34.15±0.07^a	34.20±0^a	25.65±3.04^a	33.0±0.14^a	33.50±0.42^a
DMF	31.85±0.92	32.70±0.56^a	30.45±0.49^a	28.30±0.84^a	32.95±0.49^a	33.35±0.35^a

The values are expressed as mean ± SD of three replicates NC: normal control; DC: diabetic control; MC: diabetic with metformin only (metformin control); DMC: diabetic with metformin and CMC; DMF: diabetic with metformin; WSF of A. augusta L. ^a𝑃<0.05 compared to DM (ANOVA followed by Dunnett’s test).