Clinical Study

Assessment of the Safety and Efficacy of a Raft-Forming Alginate Reflux Suppressant (Liquid Gaviscon) for the Treatment of Heartburn during Pregnancy

Table 3

Study and normative population data for incidences of adverse events during pregnancy.

Adverse eventUKSouth Africa
StudyPopulationStudyPopulation

Perinatal mortality08/100045/100032.5/1000
Maternal mortality012.2/100000011/100000
Hypertensive disease9%10%8%10%
Eclampsia01/200001/1300
Antepartum haemorrhage3.8%2–5%3.4%2–5%
Abruptio placenta00.5–1.8%2.2%0.6%
Preterm labour3.8%5.1%5.6%11%
Caesarean section rate26%22%35%12%
Assisted vaginal deliveries23%10.5%8%5%

References from internal report by S. W. Lindow [1021].