Integrin Signaling in Mammary Epithelial Cells and Breast Cancer

Figure 1

Integrin expression in the normal mammary gland. The α and β integrin subunits expressed in the mammary gland are listed with the CD alias in parentheses. Their lineage expression pattern is indicated as L (luminal), M (myoepithelial), and L/M (luminal and myoepithelial). *indicates a relatively low-level or restricted expression pattern. The lineage expression of the β3 integrin is not clear. The functional integrin receptors and their ligand class are shown below. See [7, 10–12] for more information.