Development and Validation of HPTLC Method for Estimation of Propranolol Hydrochloride and Flunarizine Dihydrochloride in Combined Dosage Form

Table 2

Summary of validation parameters.

Parameters	PRO	FLU
Rf	0.07±0.02	0.67±0.02
Detection limit (𝜇g/ml)	118.4	13.75
Quantitation limit (𝜇g/ml)	355.2	45.4
Accuracy (%)	99.71–100.92 %	98.8–101.27
Precision (RSD^a,%)
Intraday precision (𝑛=3)	1.06–1.33	1.28–1.48
Interday precision (𝑛=3)	0.237–0.65	0.66–0.88
Instrument precision (RSD^a)	0.09	0.24

^aRSD is relative standard deviation and “𝑛” is number of determinations.