Locally Advanced Pancreatic Head Cancer: Margin-Positive Resection or Bypass?

Table 2

Perioperative outcome. 𝑃 value given for two-sided Kruskal-Wallis and Fisher’s exact test. Figures that cause a statistically significant difference are printed bold. ¹Cases with perioperative mortality excluded. R0/R+: pancreatoduodenectomy with free/positive resection margins, M0: absence of distant metastasis at laparotomy, M+: presence of distant or peritoneal metastasis at laparotomy, bypass: palliative bypass procedures.

	R0 resection	R+ resection	Bypass	𝑃 value
𝑁	172	71	117	—
Overall morbidity	91/53%	34/48%	54/46%	0.369
Surgical morbidity	60/35%	23/32%	27/23%	0.038
Severe morbidity	21/12%	9/13%	15/13%	0.867
POPF B/C	19/11%	2/3%	—	0.044
DGE B/C	21/12%	8/11%	12/10%	0.725
Postoperative bleeding	9/5%	6/9%	1/1%	0.026
RBC transfusion	76/44%	38/54%	7/6%	<0.001
Reoperation	15/9%	5/7%	11/9%	0.693
Overall mortality	7/4%	2/3%	7/6%	0.413
Surgical mortality	7/4%	2/3%	3/3%	0.758
Hospital days, median (range)^1	17 (9–62)	15 (9–61)	13 (4–80)	<0.001