Review Article
Osmotic Drug Delivery System as a Part of Modified Release Dosage Form
Table 1
List of various osmogens with their osmotic pressure [
32,
34].
| Osmotic pressures of saturated solution of commonly used osmogens | Osmotic pressure (atm) |
| Sodium chloride | 356 | Fructose 3 | 55 | Potassium chloride | 245 | Sucrose | 150 | Xylitol | 104 | Sorbitol | 84 | Dextrose | 82 | Citric acid | 69 | Tartaric acid | 67 | Mannitol | 38 | Potassium sulphate | 39 | Lactose | 23 | Fumaric acid | 10 | Adipic acid | 8 | Lactose-fructose | 500 | Dextrose-fructose | 450 | Sucrose-fructose | 430 | Mannitol-fructose | 415 | Sodium chloride | 356 | Fructose | 335 | Lactose-sucrose | 250 | Potassium chloride | 245 | Lactose-dextrose | 225 | Mannitol-dextrose | 225 | Dextrose-sucrose | 190 | Mannitol-sucrose | 170 | Sucrose | 150 | Mannitol-Lactose | 130 | Dextrose | 82 | Potassium sulphate | 39 | Mannitol | 38 | Sodium phosphate tribasic·12H2O | 36 | Sodium phosphate dibasic·7 H2O | 31 | Sodium phosphate dibasic·12 H2O | 31 | Sodium phosphate monobasic·H2O | 28 | Sodium phosphate dibasic. Anhydrous | 21 |
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