miR-320 Regulates Glucose-Induced Gene Expression in Diabetes

<table>(a) 25 mM D-glucose (HG) caused decreased miRNA-320 expression in the endothelial cells compared to 5 mM D-glucose (LG) by real-time RT-PCR. (b) Similarly, diabetes caused reduced miR-320 expression in the kidney. (miRNA expressed as a ratio of U6 snRNA (U6). <svg height="11.9" id="M3" style="vertical-align:-0.30096pt" version="1.1" viewbox="0 0 62.487499 11.9" width="62.487499" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,11.9)">
<g transform="translate(72,-62.48)">
<text transform="matrix(1,0,0,-1,-71.95,67.83)">
<tspan style="font-size: 8.75px; " x="0" y="0">∗</tspan>
</text>
<text transform="matrix(1,0,0,-1,-66.87,62.83)">
<tspan style="font-size: 12.50px; " x="0" y="0">𝑃</tspan>
<tspan style="font-size: 12.50px; " x="10.890113" y="0">&lt;</tspan>
<tspan style="font-size: 12.50px; " x="22.930502" y="0">0</tspan>
<tspan style="font-size: 12.50px; " x="29.182001" y="0">.</tspan>
<tspan style="font-size: 12.50px; " x="32.307751" y="0">0</tspan>
<tspan style="font-size: 12.50px; " x="38.559254" y="0">5</tspan>
</text>
</g>
</g>
</svg> compared to LG or control; <svg height="11.0375" id="M4" style="vertical-align:-0.17555pt" version="1.1" viewbox="0 0 35.099998 11.0375" width="35.099998" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,11.0375)">
<g transform="translate(72,-63.17)">
<text transform="matrix(1,0,0,-1,-71.95,63.4)">
<tspan style="font-size: 12.50px; " x="0" y="0">𝑛</tspan>
<tspan style="font-size: 12.50px; " x="9.6773224" y="0">=</tspan>
<tspan style="font-size: 12.50px; " x="21.71771" y="0">6</tspan>
</text>
</g>
</g>
</svg>/treatment; analyses were performed using mirVana miRNA isolation kit and TaqMan microRNA assay system).</table>

International Scholarly Research Notices

miR-320 Regulates Glucose-Induced Gene Expression in Diabetes

Figure 1