High-Grade Prostate Cancer: Favorable Results in the Modern Era Regardless of Initial Treatment

Table 3

5-year outcome measures by primary treatment.

	Surgery	Radiation	Hormone therapy	Total	𝑃^1
5-year OS, %	88.9%	76.3%	58.9%	77.5%	0.01
5-year BFFS, %	54.2%	81.4%	77.5%	65.6%	<0.001
5-year MFS, %	96.8%	96.6%	88.4%	94.1%	0.24
5-year CSS, %	97.2%	100%	89.9%	95.3%	0.8

¹OS: Overall Survival; BFFS: Biochemical Failure-Free Survival; MFS: Metastasis-Free Survival; CSS: Cancer-Specific Survival.
²Based on a logistic regression model adjusted for age, Gleason score, pretreatment PSA, and positive cores.