652739.fig.003a
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652739.fig.003b
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Figure 3: Joint damage in hTNFα-transgenic mice. Top: erosive changes in the cartilage-bone-pannus region of a proximal interphalangeal joint from a hTNFα-transgenic mouse with arthritis. Note the focal erosion of subchondral bone. Bottom: normal joint from a non-transgenic littermate. Haematoxylin and eosin.