Itraconazole Niosomes Drug Delivery System and Its Antimycotic Activity against Candida albicans

Table 5

Coefficient values obtained from multiple regression analysis.

Responses studied	Coefficients for ES60
	bo	b1	b2	b11	b12	b21	𝑅^2
Vesicle size (μm) (Y1)	26.49	5.74	−2.13	1.36	—	—	0.9970
Entrapment efficiency (%) (Y2)	85.44	−5.50	3.32	0.69	−15.92	0.71	0.9997
Time required for 50% drug release (hr) (Y3)	4.01	−0.08	—	−0.73	—	—	0.999