Research Article

Polymorphic Forms of Lamivudine: Characterization, Estimation of Transition Temperature, and Stability Studies by Thermodynamic and Spectroscopic Studies

Table 2

Thermal characteristics of Form I, Form II, Form IIH, Form IIIL, and Form IIIH of lamivudine by differential scanning calorimetry.

SampleMelting temperature
(°C)
Enthalpy of fusion
(J/g)

Form IL117.519.6
Form IH178.2109.9
Form II178.690.9
Form IIIL114.313.9
Form IIIH173.843.7