Downregulation in GATA4 and Downstream Structural and Contractile Genes in the db/db Mouse Heart
Figure 5
Cardiac α-MHC mRNA expression (a) β-MHC mRNA expression (b), and protein expression (c) in control and db/db mice. Protein expression of β-MHC was not detected in control hearts, whereas in db/db hearts, β-MHC expression was elevated. Values are expressed as mean ± SEM obtained from 2 separate experiments each performed with 5 hearts. db/+, control mice; db/db, diabetic mice. .