Metabolic and Hormonal Alterations with Diacylglycerol and Low Glycemic Index Starch during Canine Weight Loss

Table 3

Fasting and postprandial areas under the curves of plasma glucose, insulin, NEFA, and incretin hormones at weeks 1 and 8 determined at 60 and 180 minutes.

			Diet					𝑃 value
			LD	LT	HD	HT	SEM	Oil	Starch	Oil by starch
Week 1	Glucose	Fasting, mmol/L	5.2	6.0	5.9	6.0	0.2	ns	ns	ns
		AUC, 60 min	373.7	332.3	355.4	400.0	14.7	ns	ns	ns
		AUC, 180 min	1117.1	1046.8	1130.5	1261.2	42.1	ns	0.052	ns
	Insulin	Fasting, pmol/L	13.0	9.1	8.7	20.6	2.9	ns	ns	ns
		AUC, 60 min	2074.6	1392.2	3521.0	5548.6	593.0	ns	0.004	ns
		AUC 180 min	15469.2	21485.0	16328.6	18047.4	1986.9	ns	<0.001	0.032
	NEFA	Fasting, mmol/L	0.8	0.8	0.9	1.0	0.1	ns	ns	ns
		AUC, 60 min	34.3	30.4	26.0	31.8	1.7	ns	ns	ns
		AUC, 180 min	91.7	91.3	55.4	61.8	5.8	ns	0.004	ns
	GIP	Fasting, pmol/L	5.2	8.9	8.7	9.5	1.0	ns	ns	ns
		AUC, 60 min	545.2	673.3	839.1	982.5	119.4	ns	ns	ns
	GLP-1	Fasting, pmol/L	6.7	7.1	6.6	6.8	0.2	ns	ns	ns
		AUC, 60 min	453.2	502.2	508.9	494.7	13.9	ns	ns	ns
Week 8	Glucose	Fasting, mmol/L	6.0	5.9	5.8	5.6	0.2	ns	ns	ns
		AUC, 60 min	388.0	373.5	438.7	379.5	13.7	0.006	0.029	ns
		AUC, 180 min	1182.2	1140.1	1308.8	1211.5	41.5	ns	0.041	ns
	Insulin	Fasting, pmol/L	17.0	9.2	8.5	9.5	1.8	ns	ns	ns
		AUC, 60 min	2424.4	1746.2	3922.6	3470.6	375.4	ns	0.039	ns
		AUC, 180 min	18906.8	14180.1	14609.8	18047.4	1429.2	ns	0.041	ns
	NEFA	Fasting, mmol/L	1.0	0.9	1.0	1.2	0.1	ns	ns	ns
		AUC, 60 min	41.1	31.7	29.5	38.3	2.6	ns	ns	ns
		AUC, 180 min	105.7	89.2	75.2	73.6	6.6	ns	ns	ns
	GIP	Fasting, pmol/L	16.1	10.7	12.1	12.1	1.3	ns	ns	ns
		AUC, 60 min	1221.0	1047.6	1736.3	1047.6	124.4	0.045	ns	ns
	GLP-1	Fasting, pmol/L	5.6	6.4	6.3	6.0	0.2	ns	ns	ns
		AUC, 60 min	435.5^a	618.1^a	670.8^b	444.2^a	35.9	ns	ns	0.005

Mean ± SEM, 𝑛=6.; ns denotes no statistical difference. 𝑃 values are for two-way ANOVA with starch and oil as fixed factors.
Letters not in common in a row denote significant differences among diets by two-way ANOVA, 𝑃 < 0.05.