Review Article
Metastatic Squamous Cell Carcinoma of the Anus: Time for a Shift in the Treatment Paradigm?
Table 2
Case reports of single-agent chemotherapy in metastatic anal squamous cell carcinoma.
| | Author | Number of patients | Agent | Response | PFS/duration of response (months) | OS |
| | Evans et al. [16] | 1 | Carboplatin | Partial | 9 | NR | | Fisher et al. [17] | 1 | Doxorubicin and cis-dichlorodiammineplatinum | Major | NR | NR | | Zimm and Wampler [18] | 1 | Semustine | Partial | 15 | NR | | Golub et al. [19] | 3 | TIP | Complete (3/3) | 4,6,36 | NR | | Grifalchi et al. [20] | 1 | Irinotecan | Partial | NR | NR |
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