Research Article

Mechanism of Protein-Z-Mediated Inhibition of Coagulation Factor Xa by Z-Protein-Dependent Inhibitor: A Molecular Dynamic Approach

Figure 2

(a) Root mean square displacement (RMSD) of free Z-dependent protease inhibitor (ZPI) obtained in aqueous solution at 310 K and 1 atmosphere of pressure and a total time of 10 ns. (b) Root mean square fluctuation (RMSF) of all residues of free ZPI (violet), ZPI in PZ-ZPI complex (black) and in ternary complex of PZ-ZPI-FXa (orange) at 10 ns of simulation.
762728.fig.002a
(a)
762728.fig.002b
(b)