Research Article
In Vitro-In Vivo Correlation Evaluation of Generic Alfuzosin Modified Release Tablets
Table 7
Functions of excipients in reference listed drug (RLD) and developed generic product.
| Reference listed drug | Proposed developing generic drug | Function |
| Microcrystalline cellulose, NF | Lactose monohydrate, NF | Filler | Mannitol, USP | | Filler | Hydroxypropyl methylcellulose, USP | Mono- and diglycerides, NF | Rate controlling polymer | Ethylcellulose, NF | | Polymer | Colloidal silicon dioxide, NF | Colloidal silicon dioxide, NF | Glidant | Magnesium stearate | Magnisium stearate | Lubricant | Hydrogenated castor oil, NF | Talc | Lubricant | Povidone | | Solubilizer | Yellow iron oxide | | Colourant |
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