Radioactive Iodine Therapy Decreases Recurrence in Thyroid Papillary Microcarcinoma

Table 2

Logistic regression analysis for correlation of various risk factors with development of recurrent disease.

Characteristic	Number with recurrence (%)	Univariate P value	Relative risk (95% CI)	Multivariate P value
Age
≥45 years	10/207 (4.8)
<45 years	30/200 (15.0)	0.042		NS
Gender
Male	7/86 (8.1)
Female	33/321 (10.3)	0.248		NS
Multifocal tumor
Yes	20/188 (10.6)	0.462		NS
No	20/219 (9.1)
Capsular invasion
Yes	15/126 (11.9)	0.389		NS
No	25/281 (8.9)
Vascular Invasion
Yes	3/14 (21.4)	0.823		NS
No	37/393 (9.4)
Soft tissue invasion
Yes	8/68 (11.8)	0.937		NS
No	32/339 (9.4)
Positive surgical margin
Yes	8/73 (11.0)	0.654		NS
No	32/334 (9.6)
Positive lymph nodes
Yes	19/153 (12.4)	0.4266	2.3 (1.2-4.6)	0.0150
No	21/252 (8.3)
Tumor size
>0.8 cm	25/132 (18.9)	0.0104	2.1 (1.1-4.1)	0.0250
≤0.8 cm	15/275 (5.5)
I-131 therapy
No	20/51 (39.2)	<0.0001	8.6 (4.4-17.1)	<0.0001
Yes	20/349 (5.7)