Titrimetric and Spectrophotometric Assay of Ganciclovir in Pharmaceuticals Using Cerium(IV) Sulphate as the Oxidimetric Agent

Table 2

Sensitivity and regression parameters.

Parameter	Value
λ max, nm	460
Linear range, μg m^−1	2.0–10.0
Molar absorptivity (ε), L mol^−1 cm^−1	1.960 × 10^4
Sandell sensitivity*, μg cm^−1	0.0132
Limit of detection (LOD), μg m^−1	0.05
Limit of quantification (LOQ), μg m^−1	0.15
Regression equation, Y**
Intercept (a)	0.7240
Slope (b)	−0.0650
Standard deviation of a (𝑆𝑎)	0.4448
Standard deviation of b (𝑆𝑏)	0.0703
Regression coefficient (𝑟)	−0.9995

*Limit of determination as the weight in μg per mL of solution, which corresponds to an absorbance of 𝐴=0.001 measured in a cuvette of cross-sectional area 1 cm² and 𝑙 = 1 cm.  ^∗∗𝑌=𝑎+𝑏𝑋, where 𝑌 is the absorbance, 𝑋 is concentration in μg/mL, 𝑎 is intercept, and 𝑏 is slope.