Titrimetric and Spectrophotometric Assay of Ganciclovir in Pharmaceuticals Using Cerium(IV) Sulphate as the Oxidimetric Agent

Table 5

Results of analysis of tablets by the proposed methods.

Tablet brand name	Label claim, mg/tablet	Found* (percent of label claim ± SD)
		Reference method	Titrimetry	Spectrophotometry
Ganguard 500	500	100.5±0.73%	99.2±0.63	99.9±0.53
			𝑡=3.03	𝑡=0.90
			𝐹=1.33	𝐹=1.89
Nataclovir 250	250	102.3±1.40%	100.5±1.10	100.5±1.05
			𝑡=2.26	𝑡=2.30
			𝐹=1.62	𝐹=1.78

*Mean value of five determinations.
The value of 𝑡 (tabulated) at 95% confidence level and for four degrees of freedom is 2.77.
The value of 𝐹 (tabulated) at 95% confidence level and for four degrees of freedom is 6.39.