Titrimetric and Spectrophotometric Assay of Ganciclovir in Pharmaceuticals Using Cerium(IV) Sulphate as the Oxidimetric Agent

Table 6

Accuracy assessment by recovery experiments.

Method	Tablet studied	GNC tablet*	Pure GNC added*	Total found*	Pure GNC recovered**, Percent±SD
Titrimetry	Ganguard 500	3.99	2.0	6.07	102.2 + 0.85
		3.99	4.0	8.19	105.0+0.12
		3.99	6.0	10.08	102.5+0.21
	Nataclovir 250	4.10	2.0	6.10	100.1+0.34
		4.10	4.0	8.14	101.2+0.11
		4.10	6.0	10.25	103.9+0.22
Spectrophotometry	Ganguard 500	4.13	2.0	6.18	101.4+0.12
		4.13	4.0	8.34	105.2+0.90
		4.13	6.0	10.25	103.8+0.56
	Nataclovir 250	3.98	2.0	6.26	107.1+0.12
		3.98	4.0	8.20	105.7+0.80
		3.98	6.0	10.17	104.8+0.76

*Mg in titrimetry and μg mL⁻¹ in spectrophotometry.
**Mean value of three measuresments.