An Integrated Multiscale Mechanistic Model for Cancer Drug Therapy

Table 2

Baseline parameter values used for signaling pathway model.

Parameters	Baseline values	Unit	References
EGF	5.2×10^−9	mol/l	Estimated
EGFR	800,000		[20]
𝐾𝑚1	2.5×10^−9	mol/l	[20]
𝐾𝑚2	2.5×10^−9	mol/l	[20]
𝜔max	0.0143	Hour^−1	[20]
𝑑max	0.010	Hour^−1	Estimated
𝜇half	4800		[20]
𝑘𝑑	4×10^10		Estimated