Table 2: Solubility profile of etoricoxib in water-PEG 400 mixture at room temperature.

Water (% v/v)Polyethylene glycol 400 (% v/v)Dielectric constantSolubility of etoricoxib ( 𝑆 𝑚 , mg/mL) (Mean ± S.D., 𝑛 = 3 )

010012.50 2 . 1 9 1 8 ± 0 . 0 8 2 8
109019.00 2 . 0 8 4 0 ± 0 . 0 6 0 7
208025.59 1 . 7 6 6 4 ± 0 . 0 5 5 2
307032.19 1 . 4 3 1 1 ± 0 . 0 4 1 7
406038.78 1 . 1 6 8 2 ± 0 . 0 3 1 2
505045.38 0 . 8 3 2 9 ± 0 . 0 2 1 0
604051.98 0 . 6 0 4 4 ± 0 . 0 0 9 8
703058.57 0 . 3 7 5 7 ± 0 . 0 0 6 6
802065.17 0 . 2 7 0 8 ± 0 . 0 0 4 3
901071.76 0 . 1 5 9 0 ± 0 . 0 0 3 7
100078.36 0 . 0 7 6 7 ± 0 . 0 0 1 8