K-Ras Mutations in Non-Small-Cell Lung Cancer: Prognostic and Predictive Value

Table 1

Prognostic value of K-RAS mutations.

Author	Total number of patients	K-RAS mutations (%)	Survival (𝑃-value)
Tsao et al. [24]	450	26.0	0.4
Schiller et al. [25]	184	24.0	0.38
Graziano et al. [26]	213	16.4	0.33
Keohavong et al. [27]	173	32	0.74
Lu et al. [28]	94	34	0.52
Slebos et al. [29]	69	27.5	0.002*
Nelson et al. [30]	365	22.1	0.009*
Fukuyama et al. [31]	159	6.9	<0.05*
Huang et al. [32]	144	8.3	0.03*
Miyake et al. [33]	187	8.0	0.037
Marks et al. [34]	296	17%	NR

NR: not reported.*Statistically significant.