CD8 T-Cell Responses in Incident and Prevalent Human Papillomavirus Types 16 and 18 Infections

Figure 1

Natural history of HPV16 or HPV18 infection and time points at which ELISPOT assays were performed. (a) Schematic representation of an incident HPV16 or HPV18 infection which cleared one year later. (b) Schematic representation of an incident HPV16 or HPV18 infection which persisted one year later. (c) Schematic representation of a prevalent HPV16 or HPV18 infection which lasted at least four months at the time of study entry and which cleared one year later. (d) Schematic representation of a prevalent HPV16 or HPV18 infection which lasted at least four months at the time of study entry and which persisted one year later. “■”: a visit at which HPV16 or HPV18 DNA was detected. “□”: a visit at which HPV-DNA testing result was negative for HPV16 and HPV18.