Research Article

Nephroprotective Effect of POLYCAN on Acute Renal Failure Induced by Cisplatin in Rats

Table 2

Change of absolute and relative kidney weight at euthanasia.

Kidney weightSham controlVehicle controlCAPTP 31.25P 62.5P 125LOSA

Absolute weight (g) 0 . 6 4 9 ± 0 . 0 9 2 0 . 9 5 3 ± 0 . 1 1 1 * 0 . 8 4 6 ± 0 . 0 9 7 * 0 . 8 1 8 ± 0 . 0 9 6 *,## 0 . 7 9 5 ± 0 . 0 8 1 **,# 0 . 7 8 3 ± 0 . 1 4 0 ## 0 . 8 4 8 ± 0 . 0 9 5 *,##
Relative weight (%) 0 . 2 8 3 ± 0 . 0 4 5 0 . 4 5 3 ± 0 . 0 8 0 * 0 . 4 0 8 ± 0 . 0 6 4 * 0 . 3 8 4 ± 0 . 0 6 6 * 0 . 3 6 2 ± 0 . 0 2 8 *,## 0 . 3 6 1 ± 0 . 0 6 9 **,## 0 . 4 0 8 ± 0 . 0 4 5 *

𝑛 = 8 ; (Mean ± S.D.), Relative kidney weight (%) = [(Absolute kidney weight/Body weight at sacrifice) × 100]; * 𝑃 < 0 . 0 1 and ** 𝑃 < 0 . 0 5 compared to sham by MW test; # 𝑃 < 0 . 0 1 and ## 𝑃 < 0 . 0 5 compared to vehicle control by MW test.