Table 4: Change on the histomorphometry of kidney at euthanasia.

Histomorphometry1Sham controlVehicle controlCAPTP 31.25P 62.5P125LOSA

Degenerative regions 1 . 7 3 ± 1 . 6 0 7 8 . 9 2 ± 8 . 5 6 * 5 6 . 7 6 ± 1 0 . 3 6 *,# 5 4 . 7 9 ± 1 0 . 9 3 *,# 4 0 . 5 0 ± 1 2 . 9 2 *,# 3 3 . 7 3 ± 5 . 7 7 *,# 6 3 . 8 0 ± 1 0 . 2 4 *,##

𝑛 = 8 ; (Mean ± S.D.); 1All histomorphometry was conducted using automated image analyzer as degenerative regions (%/200 μm2 of kidney parenchyma); * 𝑃 < 0 . 0 1 compared to sham by MW test; # 𝑃 < 0 . 0 1 and ## 𝑃 < 0 . 0 5 compared to vehicle control by MW test.