Novel Reagents for the Spectrophotometric Determination of Isoniazid

Table 3

Results of assay of formulations.

Brand name	^aIsokin	^bSolonex
Labeled amount (mg)	300	300
(1) Using ECH
(i) Amount found* (mg)	299.5	299.0
(ii) % Label claim ± SD	99.83 ± 0.010	99.66 ± 0.018
(iii) 𝑡-test	2.23	2.48
(2) Using HPC
(i) Amount found* (mg)	299.70	299.81
(ii) % Label claim ± SD	99.90 ± 0.08	99.93 ± 0.06
(iii) 𝑡-test	1.67	1.62

^*Mean value of five determinations.
^aPfizer Ltd., India.
^bMacleods Pharmaceuticals Ltd.
Calculated Student’s 𝑡-value at 95% confidence level is 2.77.