Research Article
Formulation and In Vitro Evaluation of Ufasomes for Dermal Administration of Methotrexate
Table 1
Size and entrapment efficiency of the prepared oleic acid vesicles.
| Formulation code | Oleic acid: 5-MTX (molar ratio) | Entrapment efficiency | Particle size (nm) | PDI |
| UF-1 | 9 : 1 | () | 505 ± 15 | | UF-2 | 8 : 2 | () | 523 ± 12 | | UF-3 | 7 : 3 | (%), | 632 ± 17 | | UF-4 | 6 : 4 | () | 531 ± 16 | | UF-5 | 5 : 5 | () | 404 ± 13 | |
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UF-1,2,3-ufasomes with different molar ratio of drug.
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