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ISRN Hematology
Volume 2012 (2012), Article ID 937585, 5 pages
http://dx.doi.org/10.5402/2012/937585
Research Article

Implications of Weight and Body Mass Index for Plasma Donation and Health

1Johns Hopkins Hospital, Carnegie 415, 600 North Wolfe Street, Baltimore, MD 21287, USA
2Clinical Monitoring Research Program, SAIC-Frederick Inc., Frederick, MD 21702, USA
3National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH) Building 10, 8N234-C 10 Center Dr., MSC 1763, Bethesda, MD 20892-1763, USA

Received 2 October 2012; Accepted 20 October 2012

Academic Editors: S. Daenen and J. M. Moraleda

Copyright © 2012 Genna A. Jerrard et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

This study determined the percentage of potential plasma donors who could donate plasma in the 3 allowable plasma volume limit categories as specified by the Food and Drug Administration (FDA), as well as the association of the body mass index (BMI) of these individuals with age, blood pressure, oral temperature, and pulse. Of 315 plasma donors analyzed, 107 (34.0%) weighed between 110 and 149 lbs (50.0–67.7 kg), 89 (28.2%) weighed between 150 and174 lbs (68.2–79.1 kg), and 119 (37.8%) weighed >175 lbs (79.5 kg), theoretically allowing collection of an additional 101.4 liters (16% more plasma) from both heavier categories based on FDA standards for plasma donor quantities. BMI was positively associated with age, mean arterial pressure (MAP), and pulse (Pearson’s , 0.24, and 0.18, resp., values <0.05), but not with oral temperature. Average BMI for females was higher than for males ( , ), and BMI for African Americans was higher than for White and Asian participants ( and , resp., s <0.05). A significant association was also found in the sex by race interaction with BMI ( ). Follow-up analyses suggested a significant difference in BMI by sex among African Americans, higher BMI among African American females than Asian and White males, and higher BMI among White females than African American males ( s <0.05).