Construction of a Drug Safety Assurance Information System Based on Clinical Genotyping

Algorithm 2

Graph algorithm.

Input: drug interaction record (DI), patient’s weight (Weight), drug dose (Dose), multiplier (Mult)

Output: normal and selected patient dose-response curves, minimum effective and toxic concentration lines

(1) Create selected patient dose-response curve by calling CreateDoseCurve(DI, Weight, Dose, Mult)

(2) Create normal patient dose-response curve by calling CreateDoseCurve(DI, Weight, Dose, 1)

(3) Create minimum effective concentration line by using DI.EffectiveConcentration as Y coordinate

(4) Create minimum toxic concentration line by using DI.ToxicConcentration as Y coordinate

(5) return curves and lines