The Challenge of Delivering Therapeutic Aerosols to Asthma Patients

Table 2

Choice of inhaler devices according to the patient’s inspiratory flow and ability to coordinate inhaler actuation and inhalation. Modified from Chapman et al. [90].

Good hand-lung coordination		Poor hand-lung coordination
Inspiratory flow > 30 L/min	Inspiratory flow < 30 L/min	Inspiratory flow > 30 L/min	Inspiratory flow < 30 L/min
pMDI	pMDI	pMDI + spacer	pMDI + spacer
BAMDI	Nebuliser	BAMDI	Nebuliser
DPI	SMI	DPI	SMI
Nebuliser		Nebuliser
SMI		SMI

pMDI: pressurised metered-dose inhalers; BAMDI: breath-actuated metered-dose inhaler; DPI: dry powder inhaler; SMI: soft mist inhaler.