Sexually Transmitted Infections and Male Circumcision: A Systematic Review and Meta-Analysis

Table 6

Studies of the association between circumcision status and the prevalence of Chlamydia trachomatis.

Study	Intact +ve/−ve	Circumcised +ve/−ve	Odds ratio	95% confidence interval	Exact odds ratio	Exact confidence interval
Auvert	9/340	3/132	1.32	0.31–4.37	1.1644	0.2848–6.7884
Aynaud	8/154	1/47	2.44	0.30–20.03	2.4335	0.3125–110.6090
Cook	34/506	147/2089	0.95	0.65–1.40	0.9549	0.6293–1.4145
Dave	72/4761	12/970	1.22	0.66–2.26	1.2224	0.6554–2.4849
Diseker	72/212	240/622	0.88	0.65–1.20	0.8803	0.6382–1.2057
Fergusson	NA	NA	2.50	0.73–8.53	2.50	0.73–8.53
Ferris	30/1571	59/2294	0.74	0.48–1.16	0.7425	0.4596–1.1774
Gray et al. [44]*	71/2131	17/421	0.83	0.48–1.42	0.8252	0.4751–1.5104
Gray et al. [163]*	53/2589	15/462	0.63	0.35–1.13	0.6306	0.3466–1.2152
Hart	251/2725	330/4686	1.31	1.10–1.55	1.3079	1.0979–1.5567
Laumann	0/1118	36/1413	0.02	0.00–0.28	0.0246	0–0.1368
Lavreys	15/33	31/36	0.53	0.24–1.15	0.5308	0.2238–1.2241
Parker	37/553	45/684	1.02	0.65–1.59	1.0170	0.6303–1.6322
Richters	74/3392	116/5218	0.98	0.73–1.32	0.9813	0.7206–1.3295
Rodriguez-Diaz	41/405	20/194	0.98	0.56–1.72	0.9820	0.5452–1.8198
Random effects summary effect:					0.9099	0.72–1.15

Heterogeneity chi-square (df=12) was 35.53 (𝑃=.0007).
∗The Rakai data published in 2004 was used in calculating the summary effect odds ratio.