Sexually Transmitted Infections and Male Circumcision: A Systematic Review and Meta-Analysis

Table 8

Studies of the association between circumcision status and the prevalence of genital ulcerative disease.

Study	Intact +ve/−ve	Circumcised +ve/−ve	Odds ratio	95% confidence interval	Exact odds ratios	Exact confidence interval
Agot	133/312	93/301	1.38	1.01–1.88	1.3792	1.0020–1.9032
Barile	32/3	15/32	22.76	6.00–86.29	21.7418	5.5279–128.4283
Burundi	63/1597	17/869	2.02	1.17–3.47	2.0160	1.1564–3.6993
Bwayo	58/118	179/583	1.60	1.12–2.29	1.6000	1.0988–2.3141
Gray et al. [44]*	297/4302	65/843	0.90	0.68–1.18	0.8954	0.6751–1.2021
Gray et al. [163]*	383/4087	64/761	1.11	0.85–1.47	1.1143	0.8428–1.49261
Lavreys	13/82	46/605	2.09	1.08–4.02	2.0825	0.9888–4.1281
Newell	52/1304	18/628	1.39	0.81–2.40	1.3911	0.7926–2.5488
Seed	142/452	41/202	1.55	1.05–2.27	1.5470	1.0407–2.3358
Simonsen	23/47	35/196	2.74	1.48–5.07	2.7297	1.4016–5.2706
Telzak	239/105	211/203	2.19	1.62–2.96	2.1876	1.6056–2.9905
Tyndall	48/130	150/482	1.19	0.81–1.73	1.1862	0.7937–1.7548
Warner	492/4673	1836/33570	1.93	1.73–2.14	1.9250	1.7300–2.1378
Random effects summary effect:					1.6760	1.3926–2.0170

Heterogeneity chi-square (df=11) was 31.09 using MH (𝑃=.0011).
∗The Rakai data published in 2004 was used in calculating the summary odds ratio.