Biochemical Studies on Methylglyoxal-Mediated Glycated Histones: Implications for Presence of Serum Antibodies against the Glycated Histones in Patients with Type 1 Diabetes Mellitus

<table>SDS-PAGE (15%) of native histone (lane 1) and histone modified with 1 and 2 mM methylglyoxal (lanes 2 and 3, resp.) and 1 and 2 mM glyoxal (lanes 4 and 5, resp.). Electrophoresis was carried out for 3 h at 80 volts and the gel was visualized using silver staining.</table>

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Figure 1: Biochemical Studies on Methylglyoxal-Mediated Glycated Histones: Implications for Presence of Serum Antibodies against the Glycated Histones in Patients with Type 1 Diabetes Mellitus 

Figure 1 | Biochemical Studies on Methylglyoxal-Mediated Glycated Histones: Implications for Presence of Serum Antibodies against the Glycated Histones in Patients with Type 1 Diabetes Mellitus 