Research Article

Biochemical Studies on Methylglyoxal-Mediated Glycated Histones: Implications for Presence of Serum Antibodies against the Glycated Histones in Patients with Type 1 Diabetes Mellitus

Table 2

Prominent FTIR amide I bands in secondary structure of histone modified with methylglyoxal (MG).

Random coil Helix
(in cm−1)
Sheet

Histonen16411622
MG-modified histonea167416431605

n: native histone.
a represents 2 mM concentration of the histone modifiers.